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In order to improve our understanding of the epidemiology and impact of liver disease, and to enhance our ability to institute effective means of diagnosis, therapy, and prevention of liver disease at the population level, the establishment of a well-designed research database with adequate funding is crucial. Additionally, an appropriate organizational structure, staffed with qualified personnel, is a key ingredient to accomplish such objectives.


Although some of these requirements are already in place, a continued ...... Read more

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King Saud University Liver Disease Center





















SOLID  "The Systematic Observatory Liver-Diseases Registries" project is a multinational, multi-center, observational, open-label group of medical registries designed to electronically capture data, manage, monitor, and  report in liver disease

patients' outcomes treated in SOLID participated Saudi Arabian and Canadian medical centers from across all designated regions.

The main goal of SOLID registries is to collect sufficient data and accumulate experience related to the most common liver diseases seen within the two countries, to evaluate current clinical practices, identify opportunities to improve the quality-of-care for patients with liver disease, facilitate clinical research by providing data, help develop diagnostic and therapeutic clinical guidelines and provide real-life information for healthcare planners for a precise estimation of diseases' burdens and future needs and costs.

SOLID registries are designed to be a non-experimental studies, where all enrolled patients are expected to be treated according to current routine hospital practices and standards of care.

Project Description

Chronic liver disease is a significant healthcare problem and constitutes a major cause of morbidity and mortality. The economic burden imposed by liver disease on the healthcare system is

 substantial, and the problem is ...... Read more

SOLID Medical Centers



CENTRAL ZONE   ::    King Khalid University Hospital, King Saud University,  Riyadh                                                                                Riyadh Miliatry Hospital,  Riyadh                                                                                                                         King Abdulaziz Medical City, Riyadh                                                                                                                King Saud Medical Complex,  Riyadh                                                                                                                 Advanced Medicine Center,  Riyadh                                                                                                  WESTERN ZONE ::          King Fahad General Hospital,  Jeddah                                                     EASTERN ZONE ::          King Fahd Specialist Hospital, Dammam                                                                                                                          King Fahad Hospital of the University,  Khobar



Quebec               ::     MUHC - McGill University Health Center,  Montréal                                                                                                 Alberta     ::       University Of Calgary - Faculty of Medicine and Alberta Health Services Institutes and Centres,  Calgary


Ethical Considerations

An ethics approval letter will be obtained from the ethics committee of each individual participated hospital.  Despite the fact that patients' names & identities are unidentified during SOLID research  and all submitted data will remain encrypted from data entry to data analysis and publications,  A consent form is to be collected from each individual patient enrolled in the registry




Organization Structure

Several medical entities are integrated in SOLID registries and represented by certain coordinating centers, steering committees, participating hospitals, co-investigators, research assistants, and database coordinators.

The Saudi Arabian coordinating center is located in the Liver Disease Research Center, King Saud University - Riyadh. and is chaired by the doctors:  Ayman Abdo, Faisal Sanai and Mazen Hassanain.

While in Canada, two independent coordinating centers are joining SOLID:  McGill University Health Center (MUHC), Montréal - Quebec. and University Of Calgary / Faculty of Medicine and Alberta Health Services Institutes and Centers, Calgary - Alberta.

SOLID Registry Diseases

Four major liver diseases are included in SOLID project :

- Hepatitis B

- Hepatitis C

- Hepatocellular Carcinoma

- Nonalcoholic Fatty Liver Disease

Each liver disease is individually researched & has its own electronic registry.

The integrity of those registries will yield a significant database, resulting in better informed  judgments and decisions about the appropriate hepatic care to reduce disease related morbidity and mortality.


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